Liver Cancer Risk from Internally-Deposited Radionuclides-208CA398

Report No. 135 (2001) updates the liver cancer risk of Thorotrast in humans. Thorotrast, a radiographic contrast medium containing naturally occurring radionuclides of thorium was widely used in the first half of the twentieth century. An increased incidence of liver cancer in this population of patients has been known for some time. Utilizing data on the liver cancer risk of Thorotrast and of low-LET radiations in animals, the liver cancer risk of low-LET radiation in humans is also estimated.